Invitation
to the PremUp Symposium

Dear Friends and Colleagues,

You are cordially invited to attend the PremUp foundation's international scientific symposium in the reception room of the Hotel de Ville, Paris, on Friday 1st April 2011.

Despite considerable obstetric and neonatal advances in the care of very low birth weight neonates, bronchopulmonary dysplasia (BPD) continues to occur among 20 to 40% of surviving infants, and new ways for combating this disease must be found. BPD appears to result from arrested lung development, and is characterized by deficient alveolar septation and abnormal microvascular maturation. However, much of the research carried out on BPD prevention is hampered by our insufficient understanding of the specific control of distal lung development in humans.
This symposium will provide an update on the latest advances in the molecular control of distal lung development. There is also accumulating evidence that genetic factors could affect susceptibility to BPD. This may permit alternative approaches to understanding the basic pathophysiology and treatment of BPD. Prevention of BPD remains a major objective in these very premature infants.

The symposium will discuss the different possible therapeutic approaches, including the most promising for the future.

This event will also provide an opportunity for young researchers, supported by the PremUp foundation and working in this field to present their most recent research work.

Prof Pierre Henri Jarreau,
Professor of Pediatrics,
Department of Neonatal Medecine
of Port Royal,
Hôpital Cochin, Inserm U 767
University of Paris Descartes
Prof Christophe Delacourt,
Professor of pediatric pulmonology,
University Paris Descartes
Inserm U 955, Créteil